We are inviting application from enthusiastic post-doctoral candidate to participate in our project supported by the French National Agency (ANR), 2-year position – possible extension. The research program centers on the innate immune response
against viral infection.
Type I interferons are first line of host defense to protect against viral infections. The most robust producer cell type is the plasmacytoid dendritic cell (pDC). We aim at defining how IFN-I response control viral infection.
Dengue virus serve as primary viral model for our project, yet our main findings are studied to other viruses to define the broad versus virus-specific regulation. More recently, we have initiated research on SARS-CoV2.
• Originality: answer question on the host/pathogen interactions using approaches from disparate fields, cellular biology, immunology and virology.
• Well-positioned to carry out studies from molecular to organism levels.
• Part of CIRI: a center for infectious disease research, promoting an integrated approach
• State-of-the-art facilities for imaging, FACS, etc..
• Biosafety Level 3 laboratories and animal housing.
• ENS, Campus Charles Mérieux (http://www.sfrbiosciences.fr/): endowed with strong basic biology sciences.
• Strong background in cell biology and immunology.
• Prior experiences in in vivo mouse studies and/or imaging/microscopy techniques is highly advantageous.
• Self-motivation, flexibility, curious and enthusiastic to work in a collaborative team.
• Proven ability to identify key research objectives
• Written and communication skills in English
Team lead by Dr M. Dreux at the CIRI
Please send one PDF file to Marlene Dreux containing the following:
– cover letter (with short statement of the research interests)
– concise summary of previous research training
– curriculum vitae including publication list and contact details for 3 referees.
Position available as soon as October 2020